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TG 100801 Hydrochloride Chemical Structure

TG 100801 Hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP25254CAS No. :1018069-81-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1018069-81-2 Cat. No. BCP25254
Name TG 100801 Hydrochloride
Synonyms TG-100801 Hydrochloride;TG100801 Hydrochloride;
SMILES
Chemical Name
Formula C33H31Cl2N5O3 M. Wt 616.54
Purity 98% Storage Store at 4-8°C
Description TG 100801 Hydrochloride is a prodrug that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively.
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