BMS-777607 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP02303CAS号：1025720-94-8纯度：98%

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CAS号	1025720-94-8	货号	BCP02303
关联产品	1196681-44-3 （BMS 777607）
中文名	BMS-777607
英文名	BMS-777607
中文别名
英文别名	1196681-44-3;BMS817378; BMS 817378; BMS-817378; BMS777607;BMS 777607; ASLAN 002; ASLAN-002; ASLAN002;
SMILES	O=C(NC1=CC=C(C(F)=C1)OC2=C(C(N)=NC=C2)Cl)C3=C(C=CN(C3=O)C4=CC=C(C=C4)F)OCC
化学名称
分子式	C25H19ClF2N4O4	分子量	512.89
纯度	98%	配送	惯例下常温包邮
产品描述	BMS-777607, also known as BMS-817378 and ASLAN-002, a Met tyrosine kinase inhibitor, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.