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Cabotegravir Chemical Structure

Cabotegravir

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08631CAS No. :1051375-10-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1051375-10-0 Cat. No. BCP08631
Name Cabotegravir
Synonyms GSK1265744;GSK-1265744;GSK1265744;
SMILES CC1COC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
Chemical Name
Formula C19H17F2N3O5 M. Wt 405.35
Purity 98% Storage Store at 4-8°C
Description Cabotegravir is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIVADA, OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS.
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