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LY345899 Chemical Structure

LY345899

Data Sheet For research use only. Not for human use.
Cat. No. :BCP35611CAS No. :10538-99-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 10538-99-5 Cat. No. BCP35611
Name LY345899
Synonyms LY-345899; LY 345899;
SMILES C1C2CN(C(=O)N2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)NC(CCC(=O)O)C(=O)O
Chemical Name
Formula C20H21N7O7 M. Wt 471.43
Purity 98% Storage Store at 4-8°C
Description LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1.
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