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CAS No. | 1093108-50-9 | Cat. No. | BCP30656 |
Name | BI-671800 | ||
Synonyms | AP-761;AP761; AP 761;BI 671800; BI671800; | ||
SMILES | CN(C)C1=C(C(=NC(=N1)CC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C(F)(F)F)N(C)C)CC(=O)O | ||
Chemical Name | |||
Formula | C25H26F3N5O3 | M. Wt | 501.50 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma. |
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