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BI-671800 Chemical Structure

BI-671800

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30656CAS No. :1093108-50-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1093108-50-9 Cat. No. BCP30656
Name BI-671800
Synonyms AP-761;AP761; AP 761;BI 671800; BI671800;
SMILES CN(C)C1=C(C(=NC(=N1)CC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C(F)(F)F)N(C)C)CC(=O)O
Chemical Name
Formula C25H26F3N5O3 M. Wt 501.50
Purity 98% Storage Store at 4-8°C
Description BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma.
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