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| CAS号 | 1123837-84-2 | 货号 | BCP29099 |
| 中文名 | 司曲替尼 | ||
| 英文名 | Sitravatinib | ||
| 中文别名 | |||
| 英文别名 | MGCD516; MGCD-516; MGCD 516; MG516; MG 516; MG-516; | ||
| SMILES | COCCNCC1=CN=C(C=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F | ||
| 化学名称 | |||
| 分子式 | C33H29F2N5O4S | 分子量 | 629.68 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Sitravatinib, also known as MGCD516 or MG516, is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth. MGCD516 treatment resulted in significant blockade of phosphorylation of potential driver RTKs and induced potent anti-proliferative effects in vitro. MGCD516 treatment of tumor xenografts in vivo resulted in significant suppression of tumor growth. | ||
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