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Glesatinib hydrochloride Chemical Structure

Glesatinib hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP18872CAS No. :1123838-51-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1123838-51-6 Cat. No. BCP18872
Name Glesatinib hydrochloride
Synonyms MGCD265 hydrochloride;MGCD 265 hydrochloride;MGCD-265 hydrochloride;
SMILES
Chemical Name
Formula C31H27ClF2N5O3S2X M. Wt 655.16
Purity 98% Storage Store at 4-8°C
Description Glesatinib hydrochloride is an inhibitor of the MET and Axl receptor tyrosine kinase pathways, which drive tumour growth when altered. Glesatinib, also known as MGCD-265, is an orally bioavailable, small-molecule, multitargeted tyrosine kinase inhibitor with potential antineoplastic activity. MGCD265 binds to and inhibits the phosphorylation of several receptor tyrosine kinases (RTKs), including the c-Met receptor (hepatocyte growth factor receptor); the Tek/Tie-2 receptor; vascular endothelial growth factor receptor (VEGFR) types 1, 2, and 3; and the macrophage-stimulating 1 receptor (MST1R or RON).
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