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Tezacaftor 结构式

替扎卡托

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货号 :BCP07173CAS号 :1152311-62-0纯度:98%
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  • 基本信息与产品描述
CAS号 1152311-62-0 货号 BCP07173
中文名 替扎卡托
英文名 Tezacaftor
中文别名
英文别名 VX 661; VX661;VX-661;
SMILES O=C(C1(C2=CC=C(OC(F)(F)O3)C3=C2)CC1)NC4=CC5=C(N(C[C@@H](O)CO)C(C(C)(C)CO)=C5)C=C4F
化学名称
分子式 C26H27F3N2O6 分子量 520.5
纯度 98% 配送 惯例下常温包邮
产品描述 VX-661 is CFTR modulator. VX-661 is potentially useful for treatment of cystic fibrosis disease. Cystic fibrosis (CF) is a genetic disease caused by defects in the CF transmembrane regulator (CFTR) gene, which encodes an epithelial chloride channel. The most common mutation, Δ508CFTR, produces a protein that is misfolded and does not reach the cell membrane. VX-661 can correct trafficking of Δ508CFTR and partially restore chloride channel activity.
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