BI-224436 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1155419-89-8 | Cat. No. | BCP26024 |
| Name | BI-224436 | ||
| Synonyms | BI 224436; BI224436; | ||
| SMILES | CC1=NC2=CC=CC=C2C(=C1C(C(=O)O)OC(C)(C)C)C3=C4C5=C(C=C3)OCCC5=CC=N4 | ||
| Chemical Name | |||
| Formula | C27H26N2O4 | M. Wt | 442.51 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BI 224436 is an investigational new drug under development for the treatment of HIV infection. BI 224436 is the first non-catalytic site integrase inhibitor (NCINI). It inhibits HIV replication via binding to a conserved allosteric pocket of the HIV integrase enzyme. This makes the drug distinct in mechanism of action compared to raltegravir and elvitegravir, which bind at the catalytic site. | ||
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