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TIS108 Chemical Structure

TIS108

Data Sheet For research use only. Not for human use.
Cat. No. :BCP36705CAS No. :1315459-30-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1315459-30-3 Cat. No. BCP36705
Name TIS108
Synonyms TIS-108;TIS 108;
SMILES C1=CC=C(C=C1)C(=O)C(CCCCOC2=CC=CC=C2)N3C=NC=N3
Chemical Name
Formula C20H21N3O2 M. Wt 335.4
Purity 98% Storage Store at 4-8°C
Description TIS108 is a triazole-type strigolactone (SL)-biosynthesis inhibitor that reduces the level of 2'-epi-5-deoxystrigol (epi-5DS) in rice. Here we report the effects of TIS108 on Arabidopsis. Treatment of TIS108 increased the number of branches and repressed root hair elongation as was observed in SL-deficient mutants, and co-application of GR24, a synthetic SL analog, recovered the TIS108-induced phenotype to that of wild-type. In addition, MAX3 and MAX4 genes in the SL-biosynthesis pathway were upregulated in TIS108-treated Arabidopsis, probably due to feedback regulation caused by SL deficiency. These results indicate that TIS108 is an effective tool for regulating SL production in Arabidopsis.
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