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CAS No. | 13299-99-5 | Cat. No. | BCP35481 |
Name | AG-270 HCl | ||
Synonyms | AG-270;MAT2A inhibitor 2;RUN99995; RUN-99995; RUN 99995;AG 270;AG270; | ||
SMILES | O=C1C(C)=CC(C2=CC=CC(OC)=C2)=NN1CCN3CCOCC3.[H]Cl | ||
Chemical Name | |||
Formula | C18H24ClN3O3 | M. Wt | 365.86 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AG-270 is a potent and orally active MAT2A inhibitor with potential antineoplastic activity. AG-270 inhibits the activity of MAT2A, a metabolic enzyme responsible for the production of S-Adenosyl-L-methionine (SAM), a primary donor of methyl groups in cellular transmethylation reactions that regulate gene expression, cell growth, and differentiation. |
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