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Agomelatine Chemical Structure

Agomelatine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02084CAS No. :138112-76-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 138112-76-2 Cat. No. BCP02084
Name Agomelatine
Synonyms Valdoxan;Melitor;Thymanax;
SMILES
Chemical Name
Formula C15H17NO2 M. Wt 243.3
Purity 98% Storage Store at 4-8°C
Description Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 5-HT2C results in an enhancement of DA and NE release and activity of frontocortical dopaminergic and adrenergic pathways. Agomelatine is also a potent agonist at melatonin receptors which makes it the first melatonergic antidepressant.
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