MRX-2843 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1429882-07-4 | Cat. No. | BCP30180 |
| Name | MRX-2843 | ||
| Synonyms | UNC2371;UNC-2371;UNC 2371;MRX 2843 ;MRX2843; | ||
| SMILES | CN1CCN(CC1)CC2=CC=C(C=C2)C3=CN(C4=NC(=NC=C34)NCCC5CC5)C6CCC(CC6)O | ||
| Chemical Name | |||
| Formula | C29H40N6O | M. Wt | 488.68 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MRX-2843 is a type 1 small-molecule tyrosine kinase inhibitor that abrogates activation of both MERTK and FLT3 and their downstream effectors. MRX-2843 treatment induces apoptosis and inhibits colony formation in AML cell lines and primary patient samples expressing MERTK and/or FLT3-ITD, with a wide therapeutic window compared with that of normal human cord blood cells. | ||
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