Adavivint New
Data Sheet
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| CAS No. | 1467013-03-3 | Cat. No. | BCP36799 |
| Name | Adavivint | ||
| Synonyms | SM04690; SM-04690; SM 04690;Lorecivivint; | ||
| SMILES | CC(C)CC(=O)NC1=CN=CC(=C1)C2=CC3=C(C=C2)NN=C3C4=NC5=C(N4)C=NC=C5C6=CC(=CC=C6)F | ||
| Chemical Name | |||
| Formula | C29H24FN7O | M. Wt | 505.56 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Adavivint is a potent and specific inhibitor of canonical Wnt signaling with an EC50 of 19.5 nM for inhibiting the TCF/LEF reporter. Adavivint enhances aggregation of human mesenchymal stem cells (hMSCs) with an EC50 of 10 nM. Adavivint (30 nM) protects chondrocytes from catabolic breakdown in vitro. | ||
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