Umbralisib hydrochloride New
Data Sheet
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| CAS No. | 1532533-78-0 | Cat. No. | BCP24682 |
| Name | Umbralisib hydrochloride | ||
| Synonyms | RP5264 hydrochloride;TGR-1202 hydrochloride;TGR 1202 hydrochloride; TGR1202 hydrochloride; TGR-1202 HCl; TGR 1202 HCl; TGR1202 HCl; | ||
| SMILES | CC(C)OC1=C(C=C(C=C1)C2=NN(C3=NC=NC(=C23)N)C(C)C4=C(C(=O)C5=C(O4)C=CC(=C5)F)C6=CC(=CC=C6)F)F.Cl | ||
| Chemical Name | |||
| Formula | C31H25ClF3N5O3 | M. Wt | 608.01 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Umbralisib hydrochloride is a novel PI3Kδ inhibitor, with IC50 and EC50 of 22.2 nM and 24.3 nM, respectively; Umbralisib hydrochloride (TGR-1202 hydrochloride) is also active against CK1ε, with an EC50 value of 6.0 μM. | ||
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