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LG100268 Chemical Structure

LG100268

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08283CAS No. :153559-76-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 153559-76-3 Cat. No. BCP08283
Name LG100268
Synonyms LG 100268 ; LG-100268;
SMILES CC1=C(C=C2C(=C1)C(CCC2(C)C)(C)C)C3(CC3)C4=NC=C(C=C4)C(=O)O
Chemical Name
Formula C24H29NO2 M. Wt 363.49
Purity 98% Storage Store at 4-8°C
Description LG100268 is a potent and selective retinoid X receptor (RXR) agonist (EC50 = 4 nM). Displays >1000-fold selectivity for RXR over RAR. Activates RXR homodimers to induce transcriptional activation. Induces tissue transglutaminase (TGase) activity in HL-60 human promyelocytic leukemia cell line. Also activates RXR/PPARγ heterodimers.
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