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Sodium Butyrate Chemical Structure

Sodium Butyrate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP31813CAS No. :156-54-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 156-54-7 Cat. No. BCP31813
Name Sodium Butyrate
Synonyms Butyric acid sodium salt;
SMILES CCCC(=O)[O-].[Na+]
Chemical Name
Formula C4H7NaO2 M. Wt 110.09
Purity 98% Storage Store at 4-8°C
Description Sodium Butyrate is the sodium salt of butyrate with potential antineoplastic activity. Butyrate, a short chain fatty acid, competitively binds to the zinc sites of class I and II histone deacetylases (HDACs). This binding affects hyperacetylation of histones, resulting in a modified DNA conformation, which subsequently leads to the uncoiling or relaxing of chromatin. Enhanced accessibility of chromatin to transcription-regulatory complexes leads to increased transcriptional activation of various epigenetically suppressed genes. Butyrate, a HDAC inhibitor, induces cell cycle arrest in G1 or G2/M and also increases the expression of other genes and proteins involved in cellular differentiation and apoptotic signaling.
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