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TX1-85-1 Chemical Structure

TX1-85-1

Data Sheet For research use only. Not for human use.
Cat. No. :BCP37896CAS No. :1603845-32-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1603845-32-4 Cat. No. BCP37896
Name TX1-85-1
Synonyms
SMILES CC(=O)N1CCN(CC1)C2CCC(CC2)N3C4=NC=NC(=C4C(=N3)C5=CC(=C(C=C5)OC6=CC=CC=C6)NC(=O)C=C)N
Chemical Name
Formula C32H36N8O3 M. Wt 580.68
Purity 98% Storage Store at 4-8°C
Description TX1-85-1 is an inhibitor of the epidermal growth factor receptor tyrosine kinase ErbB3 (IC50 = 23 nM). It is the first selective HER3 ligand that interacts with cys721 in the ATP-binding pocket of HER3.
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