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CC-90003 Chemical Structure

CC-90003

Data Sheet For research use only. Not for human use.
Cat. No. :BCP23624CAS No. :1621999-82-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1621999-82-3 Cat. No. BCP23624
Name CC-90003
Synonyms CC 90003; CC90003;
SMILES CC1=CC(=C(C=C1)NC2=NC(=NC=C2C(F)(F)F)NC3=CC(=NC=C3C)OC)NC(=O)C=C
Chemical Name
Formula C22H21F3N6O2 M. Wt 458.44
Purity 98% Storage Store at 4-8°C
Description CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, CC-90003 inhibits ERK activity, and prevents the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.
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