INCB054329 New
Data Sheet
For research use only. Not for human use.
Get Quotation Now Tel: 0086-13026320035 or orders@biochempartner.com
Real-Time Inquiry ×
* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1628607-64-6 | Cat. No. | BCP30303 |
| Name | INCB054329 | ||
| Synonyms | INCB-054329; INCB 054329; INCB54329; INCB 54329; INCB-54329; | ||
| SMILES | CC1=C(C(=NO1)C)C2=C3C4=C(C=C2)NC(=O)N4C(CO3)C5=CC=CC=N5 | ||
| Chemical Name | |||
| Formula | C19H16N4O3 | M. Wt | 348.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | INCB054329, also known as INCB-54329, is a potent and selective BET protein inhibitor that targets BD1 and BD2 of BRD2, BRD3 and BRD4. In a panel of colon cancer cell lines, more than 50% are sensitive to INCB054329 treatment with IC50 values below 500 nM in cell proliferation assays. INCB054329 down-regulated c-Myc expression, and induced cell cycle arrest and apoptosis in sensitive colon cancer cell lines. Moreover, INCB54329 was efficacious in the RKO colon cancer xenograft model. INCB054329 as a single agent or in combination with other targeted therapies is potential useful for the treatment of colon cancer. | ||
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.
Recommend Products
More >
Tags:INCB054329 supplier,INCB054329 purchase,INCB054329 manufacturer,INCB054329 distributor,INCB054329 cost,INCB054329 buy,INCB054329 for sale