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Chebulanin Chemical Structure

Chebulanin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP28487CAS No. :166833-80-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 166833-80-3 Cat. No. BCP28487
Name Chebulanin
Synonyms Terminalic acid;
SMILES C1=C(C=C(C(=C1O)O)O)C(=O)OC2C3C(C(C(O2)CO)OC(=O)C(C4C(C(=O)OC5=C4C(=CC(=C5O)O)C(=O)O3)O)CC(=O)O)O
Chemical Name
Formula C27H24O19 M. Wt 652.47
Purity 98% Storage Store at 4-8°C
Description Chebulanin is a topoisomerase I inhibitor. Chebulanin inhibits the calcineurin pathway in C. neoformans.Chebulanin exhibits potent antifungal activity against various human pathogenic fungi with minimum inhibitory concentrations ranging from 0.25 to over 64 μg/ml. Chebulanin suppresses the expression of inflammatory mediators and prevents cartilage destruction and bone erosion in mice, therefore, chebulanin is a strong therapeutic alternative for the treatment of rheumatism arthritis.Chebulanin shows strong radical scavenging activity, good potency to chelate Fe2⁺ and good inhibition ability of lipid peroxidation. Chebulanin has apparent capacities of inhibiting the survival of MCF-7 human cancer cell line.
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