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NSC781406 结构式

NSC781406

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP20676CAS号 :1676893-24-5纯度:
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  • 基本信息与产品描述
CAS号 1676893-24-5 货号 BCP20676
中文名 NSC781406
英文名 NSC781406
中文别名
英文别名
SMILES
化学名称
分子式 C29H27F2N6O6S2 分子量 627.68
纯度 配送 惯例下常温包邮
产品描述 NSC781406 demonstrates potent PI3K inhibition (PI3Kα IC50=2.0 nM) that translates into BEL-7404 cells proliferation inhibition (IC50=20 nM). NSC781406 displays reasonable liver microsome stability. NSC781406 demonstrates cytotoxic activities against leukemia, non-small cell, lung cancer, colon cancer, central nervous system cancer, melanoma, ovarian cancer, renal cancer, prostate cancer, and breast cancer. It is potent against 60 cancer cell lines with a mean GI50 value of 65 nM, and with a GI50 value less than 10 nM against four cancer cell lines.
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