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Rineterkib Chemical Structure

Rineterkib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP38204CAS No. ：1715025-32-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1715025-32-3 Cat. No. BCP38204
Name Rineterkib
Synonyms ERK-IN-1; ERK IN 1; ERK IN-1; ERK-IN 1;
SMILES CNCC(C1=CC(=CC(=C1)Br)F)NC(=O)C2=C(C=C(C=C2)C3=NC(=CN=C3N)C4CCC(C(C4)F)O)F
Chemical Name
Formula C26H27BrF3N5O2 M. Wt 578.4
Purity 98% Storage Store at 4-8°C
Description Rineterkib is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC (non-small celllung cancer), BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovanan cancer.
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