Home   >  
Neuro Signaling Pathway
  • GPCR/G Protein
  >  
5 HT Receptor/Serotonin Receptor
  >   Rupatadine fumarate
Rupatadine fumarate Chemical Structure

Rupatadine fumarate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP05230CAS No. :182349-12-8Purity:98%
 Tel: 0086-13026320035   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

  • Chemical Properties&Biological Activity
CAS No. 182349-12-8 Cat. No. BCP05230
Related Products 158876-82-5(Rupatadine)
Name Rupatadine fumarate
Synonyms UR-12592 Fumarate;UR12592 Fumarate;UR 12592 Fumarate; Rupafin; Alergoliber; Rinialer; Pafinur; Rupax; Ralif;
SMILES
Chemical Name
Formula C26H26ClN3.C4H4O4 M. Wt 532.03
Purity 98% Storage Store at 4-8°C
Description Rupatadine inhibits both platelet-activating factor (PAF) and histamine (H1) effects through its interaction with specific receptors. Rupatadine competitively inhibits histamine-induced guinea pig ileum contraction (pA2 = 9.29 ± 0.06) without affecting contraction induced by ACh, serotonin or leukotriene D4(LTD4). It also competitively inhibits PAF-induced platelet aggregation in washed rabbit platelets (WRP) (pA2= 6.68 ± 0.08) and in human platelet-rich plasma (HPRP) (IC50 = 0.68 μM), while not affecting ADP- or arachidonic acid-induced platelet aggregation. [1] In another study, it is reported rupatadine and loratadine shows similar inhibitory effect on histamine and TNF-α release, whereas SR-27417A only exhibits inhibitory effect against TNF-α.
  • Quality Control&Technical Support
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:Rupatadine fumarate supplier,Rupatadine fumarate purchase,Rupatadine fumarate manufacturer,Rupatadine fumarate distributor,Rupatadine fumarate cost,Rupatadine fumarate buy,Rupatadine fumarate for sale

0086-13720134139