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CRT0273750 Chemical Structure

CRT0273750

Data Sheet For research use only. Not for human use.
Cat. No. :BCP42590CAS No. :1979939-16-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1979939-16-6 Cat. No. BCP42590
Name CRT0273750
Synonyms CRT 0273750; CRT-0273750;
SMILES CC(C1=CC=C(C=C1)Cl)NC(=O)CCC2=NC3=C(N2CC4=CC=C(C=C4)OC(F)(F)F)N=CC=C3
Chemical Name
Formula C25H22ClF3N4O2 M. Wt 502.92
Purity 98% Storage Store at 4-8°C
Description CRT0273750 is an autotaxin inhibitor. CRT0273750 modulates LPA levels in plasma and is suitable for in vivo studies. CRT0273750 has an unexpected binding mode in that they do not interact with the active site zinc ions but instead occupy the hydrophobic LPC pocket extending from the active site of ATX together with occupying the LPA 'exit' channel.
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