JBJ-04-125-02 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2060610-53-7 | Cat. No. | BCP32863 |
| Name | JBJ-04-125-02 | ||
| Synonyms | |||
| SMILES | O=C(NC1=NC=CS1)[C@@H](C2=CC(F)=CC=C2O)N(CC3=C4C=C(C5=CC=C(N6CCNCC6)C=C5)C=C3)C4=O | ||
| Chemical Name | |||
| Formula | C29H26FN5O3S | M. Wt | 543.61 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M. JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R/T790M/C797S signaling. JBJ-04-125-02 has anti-tumor activities. | ||
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