恩替卡韦一水合物

参考资料仅供科学研究，不可用于个人用途。

货号：BCP01930CAS号：209216-23-9纯度：98%

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CAS号	209216-23-9	货号	BCP01930
中文名	恩替卡韦一水合物
英文名	Entecavir hydrate
中文别名
英文别名	Entecavir monohydrate;
SMILES
化学名称
分子式	C12H15N5O3.H2O	分子量	295.29
纯度	98%	配送	惯例下常温包邮
产品描述	Entecavir monohydrate is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir monohydrate is a nucleoside analog (more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir monohydrate is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir). Entecavir monohydrate is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection. However, Entecavir is not active against HIV. Entecavir cumulative urinary excretion was statistically significant at 45 and 60min. CLR(4°C), CLR(37°C Control) and CLR(37°C Experiment) were 12.6, 27.6 and 36 (ml/min/kg), respectively. CLTS and TR rate (for PEPT2) were 25.3 and 9.4 (ml/min/kg). In vivo, the cumulative urinary excretion of entecavir had statistical significance at 3 and 4h with CLR(Control) and CLR(Experiment) values of 31 and 42 (ml/min/kg), respectively. The CL