SB-265610
Data Sheet
For research use only. Not for human use.
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| CAS No. | 211096-49-0 | Cat. No. | BCP28242 |
| Name | SB-265610 | ||
| Synonyms | SB 265610; SB265610; | ||
| SMILES | N#CC1=C(N=NN2)C2=C(C=C1)NC(NC(C=CC=C3)=C3Br)=O | ||
| Chemical Name | |||
| Formula | C14H9BrN6O | M. Wt | 357.17 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SB-265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 values are 3.4 and 6800 nM respectively). It inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo. | ||
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