diABZI STING agonist-1 trihydrochloride New
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CAS No. | 2138299-34-8 | Cat. No. | BCP30655 |
Name | diABZI STING agonist-1 trihydrochloride | ||
Synonyms | diABZI STING agonist-1 3HCl; | ||
SMILES | CCN1C(=CC(=N1)C)C(=O)NC2=NC3=C(N2CC=CCN4C5=C(C=C(C=C5OCCCN6CCOCC6)C(=O)N)N=C4NC(=O)C7=CC(=NN7CC)C)C(=CC(=C3)C(=O)N)OC.Cl.Cl.Cl | ||
Chemical Name | |||
Formula | C42H54Cl3N13O7 | M. Wt | 959.33 |
Purity | 98% | Storage | Store at 4-8°C |
Description | diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist.diABZI STING agonist-1 (trihydrochloride) activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting−/− mice, confirming that diABZI STING agonist-1 (trihydrochloride) STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo. |
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