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LIT-927 Chemical Structure

LIT-927

Data Sheet For research use only. Not for human use.
Cat. No. :BCP29866CAS No. :2172879-52-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2172879-52-4 Cat. No. BCP29866
Name LIT-927
Synonyms LIT 927; LIT927;
SMILES COC1=CC(=C2C=C(NC(=O)N2)C3=CC=C(C=C3)Cl)C=CC1=O
Chemical Name
Formula C17H13ClN2O3 M. Wt 328.75
Purity 98% Storage Store at 4-8°C
Description LIT-927 is a Locally and Orally Active CXCL12 Neutraligand with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia. displays a higher solubility. LIT-927 reduces eosinophil recruitment in a murine model of allergic airway hypereosinophilia. Combined with a high binding selectivity for CXCL12 over other chemokines, LIT-927 represents a powerful pharmacological tool to investigate CXCL12 physiology in vivo, and to explore the activity of chemokine neutralization in inflammatory and related diseases.
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