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CBP-IN-1 Chemical Structure

CBP-IN-1

Cat. No. :BCP31464CAS No. :2222941-37-7Purity:98%
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Synonyms CCS1477;CCS 1477;CCS-1477
CAS Number 2222941-37-7
Purity 98%
M. Wt 534.60
Formula C30H32F2N4O3
Storage Store at 4-8°C
CBP-IN-1 is a potent and selective p300/CBP bromodomain inhibitor, is targeted & differentiated from BET inhibitors in prostate cancer cell lines in vitro. Combination of CCS1477 & JQ1 resulted in a highly synergistic inhibitory effect on proliferation in normal 22Rv1 cells. Global gene expression analysis revealed significantly fewer altered genes after CCS1477 (27 up, 119 down) compared to JQ1 (196 up, 655 down).

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