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CBP-IN-1 Chemical Structure

CBP-IN-1

Data Sheet For research use only. Not for human use.
Cat. No. :BCP31464CAS No. :2222941-37-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2222941-37-7 Cat. No. BCP31464
Name CBP-IN-1
Synonyms CCS1477;CCS 1477;CCS-1477;
SMILES CC1=C(C(=NO1)C)C2=CC3=C(C=C2)N(C(=N3)C4CCCC(=O)N4C5=CC(=C(C=C5)F)F)C6CCC(CC6)OC
Chemical Name
Formula C30H32F2N4O3 M. Wt 534.60
Purity 98% Storage Store at 4-8°C
Description CBP-IN-1 is a potent and selective p300/CBP bromodomain inhibitor, is targeted & differentiated from BET inhibitors in prostate cancer cell lines in vitro. Combination of CCS1477 & JQ1 resulted in a highly synergistic inhibitory effect on proliferation in normal 22Rv1 cells. Global gene expression analysis revealed significantly fewer altered genes after CCS1477 (27 up, 119 down) compared to JQ1 (196 up, 655 down).
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