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Solabegron Chemical Structure

Solabegron

Data Sheet For research use only. Not for human use.
Cat. No. :BCP31054CAS No. :252920-94-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 252920-94-8 Cat. No. BCP31054
Name Solabegron
Synonyms GW-427353; GW 427353; GW427353; GW-427,353; GW 427,353; GW427,353;
SMILES C1=CC(=CC(=C1)C(=O)O)C2=CC(=CC=C2)NCCNCC(C3=CC(=CC=C3)Cl)O
Chemical Name
Formula C23H23ClN2O3 M. Wt 410.89
Purity 98% Storage Store at 4-8°C
Description Solabegron, also known as GW-427,353, is a selective agonist for the β3 adrenergic receptor. It is being developed for the treatment of overactive bladder and irritable bowel syndrome. It has been shown to produce visceral analgesia by releasing somatostatin from adipocytes. Solabegron decreases excitability of human enteric neurons via release of somatostatin. Solabegron evokes bladder relaxation and increases micturition reflex threshold in the dog.
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