Sparsentan New
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| CAS No. | 254740-64-2 | Cat. No. | BCP23969 |
| Name | Sparsentan | ||
| Synonyms | RE-021; RE021; RE 021; PS-433540; PS 433540; DARA-a; | ||
| SMILES | CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC | ||
| Chemical Name | |||
| Formula | C32H40N4O5S | M. Wt | 592.75 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Sparsentan is a Dual angiotensin II and endothelin A receptor antagonist. Retrophin intends to develop RE-021 for orphan indications of severe kidney diseases including Focal Segmental Glomerulosclerosis (FSGS) as well as conduct proof-of-concept studies in resistant hypertension and diabetic nephropathy. RE-021, with its unique dual blockade of angiotensin and endothelin receptors, is expected to provide meaningful clinical benefits in mitigating proteinuria in indications where there are no approved therapies. | ||
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