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Zidovudine 结构式

齐多夫定

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货号 :BCP03622CAS号 :30516-87-1纯度:98%
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  • 基本信息与产品描述
CAS号 30516-87-1 货号 BCP03622
中文名 齐多夫定
英文名 Zidovudine
中文别名
英文别名 BW A509U; BWA 509U; BWA-509U; BWA509U;Azidothymidine;AZT;ZDV;Retrovir;
SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]
化学名称
分子式 C10H13N5O5 分子量 267.24
纯度 98% 配送 惯例下常温包邮
产品描述 Zidovudine (Retrovir) is a nucleoside analog reverse transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS. Zidovudine (Retrovir) is an analog of thymidine.Like other reverse transcriptase inhibitors, Zidovudine (Retrovir) works by inhibiting the action of reverse transcriptase, the enzyme that HIV uses to make a DNA copy of its RNA. Reverse transcription is necessary for production of the viral double-stranded DNA, which is subsequently integrated into the genetic material of the infected cell. The triphosphate form also inhibits DNA polymerase used by human cells to undergo cell division, but has approximately 100-fold greater affinity for viral reverse transcriptase.
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