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JK184 Chemical Structure

JK184

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP21568CAS No. ：315703-52-7Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 315703-52-7 Cat. No. BCP21568
Name JK184
Synonyms JK-184; JK 184;
SMILES CC1=C(C2=CSC(NC3=CC=C(OCC)C=C3)=N2)N4C=CC=CC4=N1
Chemical Name
Formula C19H18N4OS M. Wt 350.44
Purity 98% Storage Store at 4-8°C
Description JK-184 is a potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM). JK184 can specially inhibit Gli in the Hedgehog (Hh) pathway, which showed great promise for cancer therapeutics.
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