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Y-27632  Dihydrochloride Hydrate Chemical Structure

Y-27632 Dihydrochloride Hydrate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP26044CAS No. :331752-47-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 331752-47-7 Cat. No. BCP26044
Related Products 146986-50-7(Y27632) 129830-38-2(Y-27632 dihydrochloride)
Name Y-27632 Dihydrochloride Hydrate
Synonyms Y-27632 monohydrate dihydrochloride;Y27632 Dihydrochloride Hydrate; Y 27632 Dihydrochloride Hydrate;
SMILES CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.O.Cl.Cl
Chemical Name
Formula C14H25Cl2N3O2 M. Wt 338.3
Purity 98% Storage Store at 4-8°C
Description Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepatic fibrosis in rats, increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium, affects initial heart myofibrillogenesis in cultured chick blastoderm, promotes the proliferation and cell cycle progression of cultured astrocyte from spinal cord.
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