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LM22B-10 Chemical Structure

LM22B-10

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30139CAS No. :342777-54-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 342777-54-2 Cat. No. BCP30139
Name LM22B-10
Synonyms LM22B 10; LM22B10; LM 22B10; LM-22B10; LM22B10;
SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)N(CCO)CCO)C3=CC=C(C=C3)Cl)N(CCO)CCO
Chemical Name
Formula C27H33ClN2O4 M. Wt 485.02
Purity 98% Storage Store at 4-8°C
Description LM22B-10 is a TrkB and TrkC agonist. LM22B-10 exhibits neurotrophic activity (EC50 = 200-300 nM). LM22B-10 improves survival and increases neurite outgrowth in hippocampal cells in vitro. LM22B-10 increased cell survival and strongly accelerated neurite outgrowth, superseding the effects of brain-derived neurotrophic factor (BDNF), NT-3 or the two combined.
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