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CAS No. | 413599-62-9 | Cat. No. | BCP30854 |
Name | ZD-4190 | ||
Synonyms | ZD 4190;ZD4190; | ||
SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Br)F)OCCN4C=CN=N4 | ||
Chemical Name | |||
Formula | C19H16BrFN6O2 | M. Wt | 459.28 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ZD-4190, a substituted 4-anilinoquinazoline, is a potent, orally available inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling, with broad-spectrum antitumor efficacy. ZD-4190 is one of a series of VEGF RTK inhibitors that may have utility in the treatment of a range of histologically diverse solid tumor types. |
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