Diphenyleneiodonium chloride
Data Sheet
For research use only. Not for human use.
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| CAS No. | 4673-26-1 | Cat. No. | BCP08692 |
| Name | Diphenyleneiodonium chloride | ||
| Synonyms | Dibenziodolium chloride; DPI;Diphenyleneiodonium chloride; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C12H8ClI | M. Wt | 314.55 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Diphenyleneiodonium Chloride is an agonist of GPR3. It activates several GPR3-mediated signal transduction pathways, including Ca(2+) mobilization, cAMP accumulation, membrane recruitment of ß-arrestin2, and receptor desensitization. Diphenyleneiodonium Chloride also acts as a potent and reversible inhibitor of nitric oxide synthetase from macrophages and endothelial cells, and inhibits other flavoenzymes such as neutrophil NADPH oxidase. | ||
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