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Geneticin Chemical Structure

Geneticin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP42047CAS No. :49863-47-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 49863-47-0 Cat. No. BCP42047
Name Geneticin
Synonyms G418;G 418;G-418;Antibiotic G 418;
SMILES CC(C1C(C(C(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)O)O)O
Chemical Name
Formula C20H40N4O10 M. Wt 496.55
Purity 98% Storage Store at 4-8°C
Description Geneticin (G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells and is commonly used in laboratory research to select genetically engineered cells. Resistance to Geneticin is conferred by the neo gene from Tn5 encoding an aminoglycoside 3‘-phosphotransferase, APH 3‘ II.
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