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Galanthaminone Chemical Structure

Galanthaminone

Data Sheet For research use only. Not for human use.
Cat. No. :BCP12248CAS No. :510-77-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 510-77-0 Cat. No. BCP12248
Name Galanthaminone
Synonyms (-)-Narwedine;Narwedin; 3-Deoxy-3-oxo-galanthamine;
SMILES
Chemical Name
Formula C17H19NO3 M. Wt 285.34
Purity 98% Storage Store at 4-8°C
Description Galanthaminone reduces the action of AChE and therefore tends to increase the concentration of acetylcholine in the brain. is also an allosteric ligand at nicotinic acetylcholine receptors. It has shown activity in modulating the nicotinic cholinergic receptors on cholinergic neurons to increase acetylcholine release. Absorption of galantamine is rapid and complete and shows linear pharmacokinetics. It is well absorbed with absolute oral bioavailability between 80 and 100%. It has a half-life of seven hours. Peak effect of inhibiting acetylcholinesterase was achieved about one hour after a single oral dose of 8 mg in some healthy volunteers.
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