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SIS3 HCl Chemical Structure

SIS3 HCl

Data Sheet For research use only. Not for human use.
Cat. No. :BCP19304CAS No. :521984-48-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 521984-48-5 Cat. No. BCP19304
Name SIS3 HCl
Synonyms SIS-3;SIS 3;
SMILES
Chemical Name
Formula C28H28ClN3O3 M. Wt 489.99
Purity 98% Storage Store at 4-8°C
Description SIS3 Reduces the TGF-β1-Dependent Increase in Phosphorylation and DNA Binding of Smad3. SIS3 has no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. SIS3 can block excessive ECM production from the TGF-β1-treated normal fibroblasts and scleroderma fibroblasts, the model of cells with autocrine TGF-β signaling in vitro.
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