Mechlorethamine hydrochloride New
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CAS No. | 55-86-7 | Cat. No. | BCP35605 |
Name | Mechlorethamine hydrochloride | ||
Synonyms | Chlormethine hydrochloride; Chlorethamine HCl;Mechlorethamine HCl; | ||
SMILES | CN(CCCl)CCCl.Cl | ||
Chemical Name | |||
Formula | C5H12Cl3N | M. Wt | 192.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Mechlorethamine Hydrochloride is the hydrochloride salt of mechlorethamine, a nitrogen mustard and an analogue of sulfur mustard, with antineoplastic and immunosuppressive activities. Mechlorethamine is metabolized to an unstable, highly reactive ethyleniminium intermediate that alkylates DNA, particularly the 7 nitrogen of guanine residues, resulting in DNA base pair mismatching, DNA interstrand crosslinking, the inhibition of DNA repair and synthesis, cell-cycle arrest, and apoptosis. This agent also exhibits lympholytic properties. |
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