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Mechlorethamine hydrochloride Chemical Structure

Mechlorethamine hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP35605CAS No. :55-86-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 55-86-7 Cat. No. BCP35605
Name Mechlorethamine hydrochloride
Synonyms Chlormethine hydrochloride; Chlorethamine HCl;Mechlorethamine HCl;
SMILES CN(CCCl)CCCl.Cl
Chemical Name
Formula C5H12Cl3N M. Wt 192.51
Purity 98% Storage Store at 4-8°C
Description Mechlorethamine Hydrochloride is the hydrochloride salt of mechlorethamine, a nitrogen mustard and an analogue of sulfur mustard, with antineoplastic and immunosuppressive activities. Mechlorethamine is metabolized to an unstable, highly reactive ethyleniminium intermediate that alkylates DNA, particularly the 7 nitrogen of guanine residues, resulting in DNA base pair mismatching, DNA interstrand crosslinking, the inhibition of DNA repair and synthesis, cell-cycle arrest, and apoptosis. This agent also exhibits lympholytic properties.
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