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Toyocamycin Chemical Structure

Toyocamycin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP38808CAS No. :606-58-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 606-58-6 Cat. No. BCP38808
Name Toyocamycin
Synonyms Vengicide; Siromycin; Cyanotubericidin; Ahygroscopin-B; Antibiotic 1037; Uramycin B; NSC 63701;
SMILES C1=C(C2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N)C#N
Chemical Name
Formula C12H13N5O4 M. Wt 291.26
Purity 98% Storage Store at 4-8°C
Description Toyocamycin is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage, with an IC50 of 80 nM. Toyocamycin (Vengicide) induces apoptosis. Toyocamycin (Vengicide) shows no effect on IRE1α auto-phosphorylation.
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