Enalapril New
Data Sheet
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| CAS No. | 75847-73-3 | Cat. No. | BCP09039 |
| Name | Enalapril | ||
| Synonyms | Gadopril; MK 421; MK-421; MK421; | ||
| SMILES | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O | ||
| Chemical Name | |||
| Formula | C20H28N2O5 | M. Wt | 376.45 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, enalapril is converted by de-esterification into its active form enalaprilat. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Enalapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. | ||
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