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Amantadine Chemical Structure

Amantadine

Cat. No. :BCP09869CAS No. :768-94-5Purity:98%
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Synonyms ADS-5102, EXP 105-1; EXP-105-1; GP 38026
CAS Number 768-94-5
Purity 98%
M. Wt 151.25
Formula C10H17N
Storage Store at 4-8°C
Amantadine is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an anti-parkinsonian drug. Amantadine is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. Amantadine probably does not inhibit MAO enzyme. Moreover, the mechanism of its antiparkinsonian effect is poorly understood.[citation needed] The drug has many effects in the brain, including release of dopamine and norepinephrine from nerve endings. It appears to be a weak NMDA receptor antagonist as well as an anticholinergic, specifically a nicotinic alpha-7 antagonist like the similar pharmaceutical memantine.

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