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JNJ-26483327 Chemical Structure

JNJ-26483327

Data Sheet For research use only. Not for human use.
Cat. No. :BCP28258CAS No. :807640-87-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 807640-87-5 Cat. No. BCP28258
Name JNJ-26483327
Synonyms JNJ26483327; JNJ 26483327; BGB102; BGB-102; BGB 102;
SMILES CN1CCCCCOC(C(OC)=C2)=CC3=C2N=CN/C3=NC4=CC(Br)=CC=C4C1
Chemical Name
Formula C22H25BrN4O2 M. Wt 457.36
Purity 98% Storage Store at 4-8°C
Description JNJ-26483327, also known as BGB102, is an orally bioavailable, small-molecule, multitargeted reversible tyrosine kinase inhibitor with potential antineoplastic activity. Multitargeted tyrosine kinase inhibitor JNJ-26483327 binds to and inhibits several members of the epidermal growth factor receptor (EGFR) family, including EGFR, HER2 and HER4; Src family kinases (Lyn, Yes, Fyn, Lck and Src); and vascular endothelial growth factor receptor type 3 (VEGFR3).
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