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DCPIB Chemical Structure

DCPIB

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30868CAS No. :82749-70-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 82749-70-0 Cat. No. BCP30868
Name DCPIB
Synonyms Dcpib;4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid;
SMILES CCCCC1(CC2=CC(=C(C(=C2C1=O)Cl)Cl)OCCCC(=O)O)C3CCCC3
Chemical Name
Formula C22H28Cl2O4 M. Wt 427.36
Purity 98% Storage Store at 4-8°C
Description DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC), voltage-dependently activates potassium channels TREK1 and TRAAK, inhibits TRESK, TASK1 and TASK3 (IC50s, 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM in CPAE cells.
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