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PRI-724 结构式

ICG-001

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货号 :BCP02465CAS号 :847591-62-2纯度:98%
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  • 基本信息与产品描述
CAS号 847591-62-2 货号 BCP02465
中文名 ICG-001
英文名 PRI-724
中文别名
英文别名 PRI724; PRI 724; ICG001 isomer; ICG-001 isomer; ICG 001 isomer;
SMILES C1CN(C2CN(C(=O)C(N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6
化学名称
分子式 C33H32N4O4 分子量 548.63
纯度 98% 配送 惯例下常温包邮
产品描述 PRI-724, an isomer or enantiomer of ICG-001, is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling pathway inhibitor PRI-724 specifically inhibits the recruiting of beta-catenin with its coactivator CBP (the binding protein of the cAMP response element-binding protein CREB); together with other transcription factors beta-catenin/CBP binds to WRE (Wnt-responsive element) and activates transcription of a wide range of target genes of Wnt/beta-catenin signaling. Note: ICG-001 and PRR-724 are not the same molecule, which are enantiomer isomers. Many vendors confused them.
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