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CAS No. | 892711-75-0 | Cat. No. | BCP31765 |
Name | CDN1163 | ||
Synonyms | CDN-1163; CDN 1163; | ||
SMILES | CC1=NC2=C(C=CC=C2NC(=O)C3=CC=C(C=C3)OC(C)C)C=C1 | ||
Chemical Name | |||
Formula | C20H20N2O2 | M. Wt | 320.39 |
Purity | 98% | Storage | Store at 4-8°C |
Description | CDN-1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA). CDN-1163 increases ER calcium content, rescues neurons from ER stress-induced cell death in vitro, and shows significant efficacy in the rat 6-hydroxydopamine (6-OHDA) model of Parkinson's disease. |
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